Status:
TERMINATED
Efficacy Study of Glyceryl-Trinitrate Patch and Parecoxib (Valdecoxib) for the Prevention of Pancreatitis After Endoscopic Retrograde Cholangiopancreatography (ERCP)
Lead Sponsor:
All India Institute of Medical Sciences
Conditions:
ERCP
Pancreatitis
Eligibility:
All Genders
18+ years
Phase:
PHASE2
PHASE3
Brief Summary
ERCP is a diagnostic and therapeutic procedure that is required in patients with suspected common bile duct stone, malignant biliary obstruction, biliary fistula, etc. Pancreatitis may occur as a comp...
Detailed Description
Acute pancreatitis represents the most common complication after ERCP. The reported incidence of this complication varies from less than 1% to 40%, but rates of about 10% are reported in most prospect...
Eligibility Criteria
Inclusion
- All patients aged 18 years and above undergoing first ERCP procedure
Exclusion
- Active acute pancreatitis,
- Lower end malignant bile duct block,
- Patients undergoing repeat procedures,including those with previous sphincterotomy
- Ongoing therapy with nitrates, calcium channel blockers, somatostatin or octreotide
- Patients with bleeding diathesis.
- Patients with chronic pancreatitis
- Patients with cardiac comorbidity
Key Trial Info
Start Date :
October 1 2003
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
September 1 2005
Estimated Enrollment :
371 Patients enrolled
Trial Details
Trial ID
NCT00419549
Start Date
October 1 2003
End Date
September 1 2005
Last Update
January 29 2009
Active Locations (1)
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1
All India Institute of Medical Sciences
New Delhi, India