Status:
COMPLETED
Metronomic Chemotherapy by Cyclophosphamide Versus Megestrol in Palliative Cancer
Lead Sponsor:
Centre Oscar Lambret
Conditions:
Cancer
Eligibility:
All Genders
18+ years
Phase:
PHASE2
Brief Summary
The scope of the trial is to assess the free progression rate at 2 months for each group of patients.
Eligibility Criteria
Inclusion
- Age \> or = 18
- PS-WHO \< or = 1
- Histologically proven cancer
- No other therapeutic proposal
- Treatment can be orally taken
- Radiologic proof of evolutive character of the disease
- Effective contraception
Exclusion
- Hypercalcemia ( Ca \> 2.65 mmol/l)
- Breast cancer
- Thrombosis or pulmonary embolism
- Dysphagia, malabsorption
- Polynuclear neutrophil leukocytes \< 1000/mm3
- Treatment with Tegretol
- Active and uncontrolled infection
- Evolutive psychiatric disease
- Pregnant or lactating woman
Key Trial Info
Start Date :
September 1 2006
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
July 1 2009
Estimated Enrollment :
88 Patients enrolled
Trial Details
Trial ID
NCT00420563
Start Date
September 1 2006
End Date
July 1 2009
Last Update
July 23 2012
Active Locations (4)
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1
Centre Oscar Lambret
Lille, France, 59020
2
Hopital Saint Vincent
Lille, France, 59020
3
Centre Hospitalier Regional - Dermatology
Lille, France, 59035
4
Centre Hospitalier Regional - Oncology
Lille, France, 59035