Status:
COMPLETED
Low Molecular Weight Heparin vs Unfractionated Heparin at Cardiac Surgery
Lead Sponsor:
G. d'Annunzio University
Conditions:
Coronary Disease
Coronary Artery Bypass Grafting
Eligibility:
All Genders
35-75 years
Phase:
NA
Brief Summary
Because the impairment of platelet function may cause excess peri-operative bleeding, pre-operative aspirin discontinuation and heparin bridging are common at cardiac surgery. We aimed to evaluate the...
Detailed Description
Since LMWH provide many pharmacokinetic advantages compared with UFH, and since they are a valid substitution for UFH in a number of settings, such as non-ST elevation acute coronary syndromes and pre...
Eligibility Criteria
Inclusion
- Patients aged 35-75 years with 3-vessel coronary artery disease (CAD)
- Candidates to elective CABG
Exclusion
- Other additional (valve, carotid, etc.) simultaneous surgery required,
- Off-pump surgery,
- Any altered liver and kidney laboratory parameters,
- A history of any haemorrhagic disorders,
- Platelet count \<100,000 and \>450.000/μL,
- Treatment with ticlopidine or clopidogrel in the last month.
Key Trial Info
Start Date :
November 1 2004
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
May 1 2005
Estimated Enrollment :
43 Patients enrolled
Trial Details
Trial ID
NCT00420667
Start Date
November 1 2004
End Date
May 1 2005
Last Update
November 14 2022
Active Locations (1)
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1
Institute of Cardiology - S. Camillo Hospital
Chieti, CH, Italy, 66100