Status:

COMPLETED

A Multicentre, Single-arm, Open-label Safety Study of Lenalidomide Plus Dexamethasone in Previously Treated Subjects With Multiple Myeloma

Lead Sponsor:

Celgene Corporation

Conditions:

Multiple Myeloma

Eligibility:

All Genders

18+ years

Phase:

PHASE3

Brief Summary

This is a multi-centre, single-arm treatment study combining lenalidomide plus high dose dexamethasone. Subjects who qualify for participation will receive lenalidomide plus high dose dexamethasone i...

Eligibility Criteria

Inclusion

  • Must be diagnosed with multiple myeloma that is progressing after at least 2 cycles of anti-myeloma treatment or that has relapsed with progressive disease after treatment.
  • Subjects must discontinue all anti-myeloma drug or non-drug therapy prior to the first dose of study drug with the exception of radiation therapy initiated prior to baseline.
  • Females of childbearing potential must agree to use two reliable forms of contraception simultaneously or to practice complete abstinence.

Exclusion

  • Pregnant or lactating females

Key Trial Info

Start Date :

November 1 2006

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

November 1 2009

Estimated Enrollment :

587 Patients enrolled

Trial Details

Trial ID

NCT00420849

Start Date

November 1 2006

End Date

November 1 2009

Last Update

May 21 2012

Active Locations (5)

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Page 1 of 2 (5 locations)

1

The Mater Private Centre for Haematology & Oncology

South Brisbane, Australia, QLD 4101

2

Wilhelminenspital

Vienna, Montlearstrasse 37, Austria, 1160

3

St James's Hospital

Dublin, Ireland

4

H. Clínico de Salamanca

Salamanca, Spain