Status:

UNKNOWN

Dutch Randomised Endovascular Aneurysm Management (DREAM-) Trial

Lead Sponsor:

UMC Utrecht

Conditions:

Abdominal Aortic Aneurysm

Eligibility:

All Genders

Phase:

NA

Brief Summary

The purpose of this trial is to assess whether the new endovascular repair technique of the abdominal aortic aneurysm (AAA) is an adequate substitute of the conventional AAA repair.

Detailed Description

After the introduction of endovascular repair of abdominal aortic aneurysms (AAA), both benefits and drawbacks of this new technique have been reported. To assess whether the new technique is an adequ...

Eligibility Criteria

Inclusion

  • Asymptomatic, infrarenal AAA that requires surgery
  • Adequate infrarenal neck
  • Other aortic-iliac anatomical configuration suitable for EVAR according to the criteria of the device to be used
  • Patient having a life expectation of at least 2 years and cleared for transabdominal intervention
  • Signed informed consent

Exclusion

  • ruptured AAA or symptomatic AAA, which requires emergency surgery
  • maximum aneurysm diameter\< 5.0 cm
  • suprarenal AAA
  • Inflammatory AAA (more than minimal wall thickening)
  • infrarenal neck unsuitable for endovascular fixation or aortic-iliac anatomic configuration otherwise unsuitable for EVAR according to criteria of the device to be used
  • bilateral retroperitoneal incision required for EVAR
  • sacrifice of both hypogastric arteries required
  • anatomical variations, i.e. horseshoe-kidney, arteries requiring reimplantation
  • patient unsuitable for laparotomy
  • administration of contrast agent not possible: proved, severe systemic reaction to contrast agent
  • active infection present
  • transplantation-patients
  • limited life expectation due to other illness (\< 2 year)
  • non-iatrogenic bleeding diathesis
  • connective tissue disease

Key Trial Info

Start Date :

November 1 2000

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

December 1 2007

Estimated Enrollment :

392 Patients enrolled

Trial Details

Trial ID

NCT00421330

Start Date

November 1 2000

End Date

December 1 2007

Last Update

June 4 2008

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