Status:

COMPLETED

A Safety and Effectiveness Study of a Single Dose of JNJ-17216498 in Patients With Narcolepsy

Lead Sponsor:

Alza Corporation, DE, USA

Conditions:

Narcolepsy

Eligibility:

All Genders

18-55 years

Phase:

PHASE2

Brief Summary

The purpose of this study is to evaluate the safety and effectiveness of JNJ-17216498 compared to modafinil and placebo in patients with narcolepsy, with and without cataplexy.

Detailed Description

This study with a new, experimental drug is being done to assess safety and tolerability, and to explore effectiveness in the treatment of narcolepsy. Approximately 64 adult patients with narcolepsy w...

Eligibility Criteria

Inclusion

  • diagnosis of narcolepsy within the past 5 years
  • good general health
  • no history or presence of drug or alcohol abuse

Exclusion

  • current use of prescription or over the counter medications including asprin or herbal supplements with the exception of acetaminophen (Tylenol)
  • use of fluoxetine (Prozac) in the past 6 weeks
  • use of Xyrem in the past 4 weeks
  • use of tobacco products in the past 3 months
  • caffeine consumption that is more than 5 cups of tea, or 3 cups of coffee or 8 cans of soda per day

Key Trial Info

Start Date :

January 1 2007

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

December 1 2007

Estimated Enrollment :

16 Patients enrolled

Trial Details

Trial ID

NCT00424931

Start Date

January 1 2007

End Date

December 1 2007

Last Update

May 23 2014

Active Locations (16)

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Page 1 of 4 (16 locations)

1

Birmingham, Alabama, United States

2

Phoenix, Arizona, United States

3

Tucson, Arizona, United States

4

San Diego, California, United States