Status:
COMPLETED
Male Circumcision for HIV Prevention in Rakai, Uganda
Lead Sponsor:
National Institute of Allergy and Infectious Diseases (NIAID)
Collaborating Sponsors:
Fogarty International Center of the National Institute of Health
Conditions:
HIV Infections
Herpesvirus 2, Human
Eligibility:
MALE
15-49 years
Phase:
PHASE3
Brief Summary
Circumcision in HIV unifected men may reduce the likelihood of becoming infected with HIV, reduce sexually transmitted infections (STIs) in men, not engender increases in sexual risk behaviors, and be...
Detailed Description
South Africa has one of the most severe and fast-growing HIV epidemics in the world. Adult male circumcision may be an effective preventive measure to slow the spread of HIV and other STIs. This study...
Eligibility Criteria
Inclusion
- HIV uninfected
- Willing to receive HIV results
- Willing to be circumcised
- Parent or guardian willing to provide informed consent if applicable
- Hemoglobin of 8 grams/dl or less
- Intend to stay in Rakai, Uganda, for at least 1 year and are available for follow-up for 1 year
Exclusion
- Already circumcised or partially circumcised
- Anatomical abnormality of the penis (e.g., hypospadias, severe phimosis) that may put the participant at risk if circumcised
- Medical conditions that require therapeutic circumcision
- Medical condition that contraindicates surgery or use of local anesthesia
Key Trial Info
Start Date :
August 1 2002
Trial Type :
INTERVENTIONAL
End Date :
December 1 2006
Estimated Enrollment :
5000 Patients enrolled
Trial Details
Trial ID
NCT00425984
Start Date
August 1 2002
End Date
December 1 2006
Last Update
August 24 2007
Active Locations (1)
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1
Rakai Health Sciences Program, P.O. Box 279
Kalisizo Town, Rakai, Uganda