Status:
COMPLETED
Cyclosporin A Eye Drop Treatment in Vernal Keratoconjunctivitis
Lead Sponsor:
Campus Bio-Medico University
Collaborating Sponsors:
University of Genova
University of Padova
Conditions:
Vernal Keratoconjunctivitis
Eligibility:
All Genders
5-50 years
Phase:
PHASE3
Brief Summary
This interventional study aims to evaluate the efficacy of Cyclosporine eye drop treatment in preventing relapses of Vernal Keratoconjunctivitis (VKC) and in treating the acute phases of the disease.
Detailed Description
Vernal keratoconjunctivitis (VKC) is a severe allergic disease, characterised by chronic ocular surface inflammation with seasonal relapses. Active phases of VKC require treatment with topical steroid...
Eligibility Criteria
Inclusion
- Patients affected by VKC will be enrolled by the three Centres involved in the project
- Diagnosis of VKC will be performed on the basis of personal and family history of systemic allergic diseases, clinical examination (presence of conjunctival tarsal and/or limbal papillae) and presence of eosinophils in the conjunctival scraping
Exclusion
- Contact lens wearers
- Patients affected by other ocular diseases
- Patients subjected to ocular surgery in the preceding 6 months
- Patients under eye drop or systemic treatments for other diseases, or
- Patients enrolled in experimental trials in the preceding 6 months
Key Trial Info
Start Date :
February 1 2007
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
October 1 2008
Estimated Enrollment :
48 Patients enrolled
Trial Details
Trial ID
NCT00426023
Start Date
February 1 2007
End Date
October 1 2008
Last Update
January 28 2009
Active Locations (3)
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1
University of Rome Campus Bio-Medico
Rome, Rome, Italy, 00155
2
University of Genova
Genova, Italy
3
University of Padua
Padua, Italy