Status:
COMPLETED
Chloroquine and Coartem for Treatment of Symptomatic Children With Plasmodium Falciparum in Guinea Bissau
Lead Sponsor:
Bandim Health Project
Conditions:
Malaria, Falciparum
Eligibility:
All Genders
6-15 years
Phase:
PHASE4
Brief Summary
This study will evaluate the efficacy of treatment with artemether-lumefantrine as compared to chloroquine in the dose of 50 mg/kg for treatment of malaria in children in Guinea-Bissau. The genetic ba...
Detailed Description
This study compares treatment of uncomplicated malaria in children in Guinea-Bissau with artemether-lumefantrine (Coartem) with that of treatment with chloroquine 50 mg/kg. Furthermore, the genetic ba...
Eligibility Criteria
Inclusion
- Children presenting at one of the health centres in the study area
- Symptoms suggestive of malaria
- At least 20 P.falciparum parasites per 200 leucocytes
- Living in the study area (to enable follow-up)
Exclusion
- Danger signs
- By the responsible doctor evaluated to need to be transferred to the national hospital as an in-patient
- Previous idiosyncratic reactions to any of the study drugs
Key Trial Info
Start Date :
December 1 2006
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
November 1 2008
Estimated Enrollment :
300 Patients enrolled
Trial Details
Trial ID
NCT00426439
Start Date
December 1 2006
End Date
November 1 2008
Last Update
January 4 2011
Active Locations (1)
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1
Bandim Health Project
Apartado 861, Bissau Region, Guinea-Bissau