Status:
COMPLETED
Spaced Versus Massed Skill Learning
Lead Sponsor:
National Institute of Neurological Disorders and Stroke (NINDS)
Conditions:
Healthy Volunteer
Eligibility:
All Genders
18-80 years
Brief Summary
This study will explore the optimum training schedule for stroke patients to learn motor skills. It will see if motor training is more effective when training sessions are distributed over time (space...
Detailed Description
In cognitive psychology, practice is most effective when training sessions are distributed over time (spaced), rather than when they are close to each other (massed). This phenomenon, thought to engag...
Eligibility Criteria
Inclusion
- INCLUSION CRITERIA: Healthy Volunteers
- Age between 18-80 years
- Able to perform tasks required by the study\<TAB\>
- Willing and able to give consent
- Have a normal physical and neurological examination
- Right Handed as assessed by the Edinburgh inventory scale (Edinburgh, 1971)
- EXCLUSION CRITERIA: Healthy Volunteers
- History of alcohol or drug abuse, and psychiatric illness such as severe depression.
- Receiving drugs acting primarily on the central nervous system, which lower the seizure threshold such as antipsychotic drugs (chlorpromazine, clozapine) or tricyclic antidepressants.
- INCLUSION AND EXCLUSION CRITERIA FOR STROKE PATIENTS:
- Patients must be between the ages of 18 and 80 years of age, inclusive. Included will be those with chronic (more than 3 months) stroke who recovered motor function to the point of being able to perform the ballistic pinch force task. Stroke patients will be recruited through the NIH Clinical Research Volunteer Program. Assessment of severity of initial hemiparesis will be taken either from patient report or medical records.
- EXCLUDED FROM THE STUDY WILL BE PATIENTS:
- with a history of severe alcohol or drug abuse, psychiatric illness like severe depression, severe language disturbances, particularly of receptive nature or with serious cognitive deficits (defined as equivalent to a mini-mental state exam (Folstein, 1976) score of 23 or less)
- with severe uncontrolled medical problems (e.g., cardiovascular disease, severe rheumatoid arthritis, active joint deformity of arthritic origin, active cancer or renal disease, any kind of end-stage pulmonary or cardiovascular disease, or a deteriorated condition due to age, uncontrolled epilepsy or others)
- with metal in the body (metal in the cranium, metal fragments from occupational exposure, surgical clips in or near the brain, cardiac or neural pacemakers, intracardiac lines, implanted medication pumps, blood vessel, cochlear or eye implants)
- with history of loss of consciousness or epilepsy
- with history of hyperthyroidism or individuals receiving drugs acting primarily on the central nervous system, which lower the seizure threshold such as antipsychotic drugs (chlorpromazine, clozapine) or tricyclic antidepressants.
Exclusion
Key Trial Info
Start Date :
January 17 2007
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
December 16 2013
Estimated Enrollment :
213 Patients enrolled
Trial Details
Trial ID
NCT00426465
Start Date
January 17 2007
End Date
December 16 2013
Last Update
December 17 2019
Active Locations (1)
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1
National Institutes of Health Clinical Center, 9000 Rockville Pike
Bethesda, Maryland, United States, 20892