Status:
COMPLETED
Radiation Therapy Using Helical Tomotherapy IMRT for Head and Neck Cancer
Lead Sponsor:
Ottawa Hospital Research Institute
Conditions:
Cancer
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
Historically, patients with stage III and IV head and neck cancer have been treated with surgery and/or radiation therapy. Based on the results of recent clinical trials, in patients not able to under...
Detailed Description
The mechanisms of action to explain the radiation-induced toxic effects resulting from the more aggressive radiation therapy treatments of head and neck cancer include the additive and synergistic inc...
Eligibility Criteria
Inclusion
- Stage II, III or IV non-metastatic histologically confirmed carcinoma of the head and neck region (Oral cavity, pharynx or larynx).
- Treatment with radical radiotherapy with or without chemotherapy
- Patients in whom definitive radiotherapy with or without planned neck dissection is the selected curative treatment
- ECOG performance status of 0, 1 or 2
Exclusion
- Previous radiotherapy to head and neck mucosa
- Patients with disabling co-morbid conditions, which do not permit effective immobilization
- Patients with severe trismus, which disallow effective assessment
- Patients in whom it is deemed necessary to commence enteric nutrition prior to the start of treatment.
Key Trial Info
Start Date :
November 1 2006
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
April 1 2012
Estimated Enrollment :
89 Patients enrolled
Trial Details
Trial ID
NCT00426504
Start Date
November 1 2006
End Date
April 1 2012
Last Update
July 30 2020
Active Locations (1)
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1
The Ottawa Hospital Regional Cancer Centre
Ottawa, Ontario, Canada, K1H 8L6