Status:

COMPLETED

Bendamustine and Bortezomib Combination Therapy in Indolent Non-Hodgkin's Lymphoma(NHL)

Lead Sponsor:

Peter Moosmann

Collaborating Sponsors:

Kantonsspital Aarau

Conditions:

Lymphoma, Non-Hodgkin

Eligibility:

All Genders

18+ years

Phase:

PHASE1

PHASE2

Brief Summary

The purpose of this study is to determine whether the combination of bendamustine and bortezomib in patients with indolent Non-Hodgkin's Lymphoma or Chronic Lymphocytic Leukemia is safe and tolerable.

Detailed Description

Bendamustin and bortezomib have been shown to be effective in the treatment of patients with indolent Non-Hodgkin's Lymphoma (NHL) and Chronic Lymphocytic Leukemia (CLL). Both compounds appear not to ...

Eligibility Criteria

Inclusion

  • Symptomatic recurrent or refractory indolent NHL or B-CLL
  • Adequate organ and bone marrow function
  • Karnofsky greater than 50%

Exclusion

  • Candidates for autologous stem cell transplantation
  • Secondary high grade lymphoma
  • Concurrent severe medical condition

Key Trial Info

Start Date :

January 1 2007

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

June 1 2009

Estimated Enrollment :

12 Patients enrolled

Trial Details

Trial ID

NCT00426855

Start Date

January 1 2007

End Date

June 1 2009

Last Update

April 3 2015

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Bendamustine and Bortezomib Combination Therapy in Indolent Non-Hodgkin's Lymphoma(NHL) | DecenTrialz