Status:
COMPLETED
Banking of Chronic Lymphocytic Leukemia Tumor Cells for Vaccine Generation
Lead Sponsor:
Dana-Farber Cancer Institute
Collaborating Sponsors:
Brigham and Women's Hospital
Conditions:
Chronic Lymphocytic Leukemia
Eligibility:
All Genders
18+ years
Phase:
PHASE1
Brief Summary
The purpose of this research study is to collect, freeze and store leukemia cells from the blood or bone marrow of patients that have advanced chronic lymphocytic leukemia (CLL) that is not in clinica...
Detailed Description
* It is important to understand that even if the participant consents to allow us to save their leukemia cells, we cannot guarantee that they will be able to receive a vaccine. First, we may not be ab...
Eligibility Criteria
Inclusion
- Ability to harvest CLL cells from peripheral blood, lymph nodes or bone marrow, defined as \> 30% involvement of bone marrow intratrabecular space, or peripheral blood lymphocytosis \> 5000/microliter, or surgically accessible lymph nodes of greater than or equal to 2cm.
- ECOG performance status 0-2
- 18 years of age or older
Exclusion
- Uncontrolled infection
- Leukemia with active CNS involvement
Key Trial Info
Start Date :
November 1 2006
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
June 1 2014
Estimated Enrollment :
65 Patients enrolled
Trial Details
Trial ID
NCT00428233
Start Date
November 1 2006
End Date
June 1 2014
Last Update
April 8 2020
Active Locations (1)
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1
Dana-Farber Cancer Institute
Boston, Massachusetts, United States, 02115