Status:
COMPLETED
Steady-State Feedback Actions of Testosterone on Luteinizing Hormone Secretion in Young and Older Men
Lead Sponsor:
Mayo Clinic
Collaborating Sponsors:
National Institutes of Health (NIH)
Conditions:
Hypogonadism
Eligibility:
MALE
18-80 years
Phase:
PHASE1
Brief Summary
This study is being done to learn how the male hormone , testosterone, affects pituitary hormones in younger and older men. The pituitary is a gland in the brain that secretes hormones, some of which ...
Detailed Description
Concentrations of bioavailable testosterone decline by 1.0-1.5% annually as men age. Reduced systemic testosterone availability is associated with decreased muscle mass, strength and aerobic capacity,...
Eligibility Criteria
Inclusion
- Healthy Men Ages 18-80
- All ethnicities eligible
- Men with indeterminate erectile dysfunction eligible with normal serum gonadotropin, total testosterone, prolactin and TSH concentrations and documented integrity of the neurovascular, cardiovascular, hepatorenal systems
Exclusion
Key Trial Info
Start Date :
February 1 2004
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
December 1 2007
Estimated Enrollment :
40 Patients enrolled
Trial Details
Trial ID
NCT00431197
Start Date
February 1 2004
End Date
December 1 2007
Last Update
January 28 2010
Active Locations (1)
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1
Mayo Clinic and Foundation
Rochester, Minnesota, United States, 55905