Status:

COMPLETED

Effect of Levodopa-Carbidopa on Visual Function in Patients With Recent-Onset Nonarteritic Anterior Ischemic Optic Neuropathy

Lead Sponsor:

Shahid Beheshti University of Medical Sciences

Conditions:

Nonarteritic Anterior Ischemic Optic Neuropathy

Eligibility:

All Genders

50+ years

Phase:

PHASE4

Brief Summary

Purpose: There are some controversies about the effect of Levodopa-Carbidopa on treatment of non-arteritic anterior ischemic optic neuropathy (NAION). This study was performed to evaluate the effect o...

Eligibility Criteria

Inclusion

  • age greater than 50 years old
  • first ophthalmic examination within 6 weeks after onset of disease
  • presence of optic disc swelling followed by optic atrophy within 6 weeks
  • altitudinal, central or generalized visual field defect
  • normal ESR

Exclusion

  • confirmed giant cell arteritis
  • history of any ocular surgeries
  • optic neuropathy due to acute bleeding
  • advanced diabetic retinopathy
  • uncontrolled glaucoma
  • any ocular disorders that cause visual acuity reduction rather than NAION

Key Trial Info

Start Date :

June 1 2002

Trial Type :

INTERVENTIONAL

End Date :

April 1 2003

Estimated Enrollment :

Patients enrolled

Trial Details

Trial ID

NCT00432393

Start Date

June 1 2002

End Date

April 1 2003

Last Update

October 20 2008

Active Locations (1)

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1

Ophthalmic research center

Tehran, Tehran Province, Iran, 1666694516