Status:

TERMINATED

Proton Beam Radiation Therapy for Intraocular and Periocular Retinoblastoma

Lead Sponsor:

M.D. Anderson Cancer Center

Conditions:

Retinoblastoma

Eligibility:

All Genders

Phase:

PHASE2

Brief Summary

The purpose of this trial is to evaluate proton beam radiation therapy as an alternative to external photon beam irradiation in children with retinoblastoma as a means of local tumor control and ocula...

Detailed Description

External photon beam radiation therapy (which is current standard of care) has been used in the treatment of retinoblastoma. It is a form of radiation therapy in which the radiation is delivered by a ...

Eligibility Criteria

Inclusion

  • Active or recurrent retinoblastoma patient eligible for treatment of external beam radiation therapy.
  • A parent or guardian who can provide informed consent to a minor or child participant.
  • No concurrent infection.
  • No contraindication for repeated general anesthesia/sedation.

Exclusion

  • Inability to return for multiple examinations under anesthesia.
  • Medical contraindication for exams under anesthesia/sedation.
  • Unreliable follow-up.

Key Trial Info

Start Date :

January 1 2007

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

February 1 2014

Estimated Enrollment :

2 Patients enrolled

Trial Details

Trial ID

NCT00432445

Start Date

January 1 2007

End Date

February 1 2014

Last Update

February 27 2015

Active Locations (1)

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UT MD Anderson Cancer Center

Houston, Texas, United States, 77030