Status:
UNKNOWN
A Study Evaluating the Effects of Lipid Lowering Treatment on Steroid Synthesis
Lead Sponsor:
Abant Izzet Baysal University
Conditions:
Coronary Heart Disease
Diabetes Mellitus
Eligibility:
All Genders
18-70 years
Phase:
PHASE4
Brief Summary
Cholesterol is the precursor of glucocorticoids, mineralocorticoids and sex steroids. Both adrenal and non-adrenal (ovarian + testicular) all steroid hormones are primarily synthesized using the LDL-c...
Detailed Description
Today atherosclerotic diseases are among the most important causes of death in the world. Epidemiological, clinical, genetic, experimental and pathological studies have clearly shown the role of lipop...
Eligibility Criteria
Inclusion
- Patients in the very high risk group according to the ATPIII guide.
Exclusion
- Patients having a major disease involving hepatic, gastrointestinal and endocrinologic diseases other than diabetes.
- Patients having a known muscle disease
- Pregnancy, breast-feeding
- Patients having a history of allergy to statins or ezetimibe
- Nephropathic patients
Key Trial Info
Start Date :
January 1 2007
Trial Type :
INTERVENTIONAL
End Date :
January 1 2008
Estimated Enrollment :
Patients enrolled
Trial Details
Trial ID
NCT00433823
Start Date
January 1 2007
End Date
January 1 2008
Last Update
February 12 2007
Active Locations (1)
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1
Bolu Izzet Baysal School of Medicine
Bolu, Turkey (Türkiye), 14280