Status:

COMPLETED

Genetic Analysis Using Blood or Bone Marrow From Participants With Neuroblastoma or Noncancerous Conditions

Lead Sponsor:

Children's Oncology Group

Collaborating Sponsors:

National Cancer Institute (NCI)

Conditions:

Localized Resectable Neuroblastoma

Localized Unresectable Neuroblastoma

Eligibility:

All Genders

Brief Summary

This laboratory study is looking at genes in participants with neuroblastoma or noncancerous conditions. Identifying genes related to cancer may help in the study of cancer. It may also help doctors p...

Detailed Description

OBJECTIVES: I. Perform a whole genome scan for association of neuroblastoma with single nucleotide polymorphisms (SNP) and SNP haplotypes. II. Identify true disease-associated SNP alleles using a cu...

Eligibility Criteria

Inclusion

  • Inclusion Criteria:
  • Patient:
  • Diagnosis of neuroblastoma
  • Banked constitutional and genomic DNA within COG-ANBL00B1 Neuroblastoma Biology protocol or another COG Biology Protocol
  • At least 1.0 ?g of DNA available
  • Control (age, race, and gender-matched):
  • No diagnosis of cancer
  • May have other conditions, including any of the following:
  • Asthma
  • Inflammatory bowel disease
  • Attention-deficit disorder
  • Obesity

Exclusion

    Key Trial Info

    Start Date :

    December 11 2006

    Trial Type :

    OBSERVATIONAL

    Allocation :

    ESTIMATED

    End Date :

    Estimated Enrollment :

    9350 Patients enrolled

    Trial Details

    Trial ID

    NCT00436696

    Start Date

    December 11 2006

    Last Update

    August 7 2018

    Active Locations (2)

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    Page 1 of 1 (2 locations)

    1

    University of Mississippi Medical Center

    Jackson, Mississippi, United States, 39216

    2

    Childrens Oncology Group

    Philadelphia, Pennsylvania, United States, 19104