Status:

UNKNOWN

Efficacy of Omega-3 Fatty Acids on Borderline Personality Disorder

Lead Sponsor:

Hospital Universitari Vall d'Hebron Research Institute

Conditions:

Borderline Personality Disorder.

Eligibility:

All Genders

18-65 years

Phase:

PHASE4

Brief Summary

Borderline Personality Disorder (BDP) is a serious mental disorder that affects about 1-2% of the general population, and it is characterized by severe psychosocial impairment and a high mortality rat...

Eligibility Criteria

Inclusion

  • Meet DSM-IV criteria for BPD assessed by the Structured Clinical Interview for DSM-IV Personality Disorders (SCID-II).
  • Clinical Global Impression of Severity for BDP \> 3.
  • Age between 18 and 65 years.
  • Be able to give informed consent for participation.
  • Place of residency compatible with the assistance to the center.
  • If woman, use of effective contraception.

Exclusion

  • Have a serious medical illness.
  • History of omacor® allergy.
  • Current diagnostic unipolar depression, bipolar disorder type I, Obsessive-Compulsive Disorder, schizophrenia and other psychotic disorders.
  • DIB-R \> 8.
  • Suicidal thinking that requires hospital admission.
  • Meet DSM-IV criteria for alcohol, benzodiazepine, opioid or psychostimulant dependence in the six months prior to trial entry.
  • Transaminase elevation within three times the upper limits of normality.
  • Treatment with stable doses of antidepressants or mood stabilizers for less than six weeks.
  • Treatment with stable doses of antipsychotics for more than 1 week in the last three months.
  • Have received electroconvulsive therapy for the six months prior to trial entry.
  • Have received DBT in the last 12 months prior to trial entry.
  • Are pregnant or nursing.
  • Have participated in any other investigational study in the last 6 months prior to trial entry.
  • Current treatment or expectation to start any treatment with drugs that may interact with the study.

Key Trial Info

Start Date :

February 1 2009

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

September 1 2011

Estimated Enrollment :

102 Patients enrolled

Trial Details

Trial ID

NCT00437099

Start Date

February 1 2009

End Date

September 1 2011

Last Update

May 27 2010

Active Locations (1)

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1

Hospital Universitari Vall d'Hebron

Barcelona, Barcelona, Spain, 08035