Status:

UNKNOWN

Relationship Between D2 Receptors SPECT and the Apomorphine Test in Patients With OH Dependence (ALC-DRD2-APO)

Lead Sponsor:

Hospital Universitari Vall d'Hebron Research Institute

Conditions:

Alcoholism

Eligibility:

MALE

25-60 years

Phase:

PHASE2

Brief Summary

OH dependence is associated with DA receptor changes. Both, the apomorphine test and the D2Rec SPECt are usefull for monitoring DA receptor status. We aimed at studying whether DA receptor hypofunctio...

Eligibility Criteria

Inclusion

  • alcohol dependence
  • alcohol dependence length at least 8 years.
  • male
  • age 25 - 60 years

Exclusion

  • other drug dependence (except nicotine dependence)
  • another major axis I psychiatric diagnosis
  • comorbid neurological disorder
  • comorbid cardiovascular disorder
  • comorbid metabolic disorder
  • brain injury
  • apomorphine allergy
  • iode allergy
  • diazepam allergy

Key Trial Info

Start Date :

January 1 2007

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

June 1 2010

Estimated Enrollment :

50 Patients enrolled

Trial Details

Trial ID

NCT00437177

Start Date

January 1 2007

End Date

June 1 2010

Last Update

April 29 2009

Active Locations (1)

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1

Psychiatry Service, Hospital Universitari Vall d'Hebron

Barcelona, Catalonia, Spain, 08036