Status:
UNKNOWN
Safety and Efficacy of Bone Marrow Cell Transplantation in Humans Myocardial Infarction
Lead Sponsor:
Azienda Unita Sanitaria Locale di Piacenza
Conditions:
Acute Myocardial Infarction
Eligibility:
All Genders
18-80 years
Phase:
PHASE1
PHASE2
Brief Summary
We will study in a prospective randomised fashion 50 patients who will be treated by intracoronary transplantation of autologous, mononuclear bone marrow cells (BMCs) in addition to standard therapy a...
Detailed Description
Experimental and clinical data suggest that bone marrow-derived cells may contribute to the healing of myocardial infarction (MI).
Eligibility Criteria
Inclusion
- Recent acute transmural anterior myocardial infarction, (in agreement with WHO)
- single left anterior descending coronary artery disease
- \<72 hour from the origin of symptoms
- successful primary angioplasty of the culprit lesion
Exclusion
- screening \>72 hours after infarction,
- cardiac shock, severe comorbidity, alcohol or drug dependency
- severe comorbidity (DM,renal or liver insufficiency)
- potential child bearing woman
- inability to provide informed consent
Key Trial Info
Start Date :
July 1 2005
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
February 1 2007
Estimated Enrollment :
50 Patients enrolled
Trial Details
Trial ID
NCT00437710
Start Date
July 1 2005
End Date
February 1 2007
Last Update
March 24 2010
Active Locations (1)
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1
G da Saliceto Hospital
Piacenza, Italy, 29100