Status:
COMPLETED
Influence of Fitness on Brain and Cognition
Lead Sponsor:
University of Illinois at Urbana-Champaign
Collaborating Sponsors:
National Institute on Aging (NIA)
Conditions:
Aging
Cognitive Ability, General
Eligibility:
All Genders
60-75 years
Brief Summary
The purpose of this study is to examine the effect of aerobic fitness training on human cognition, brain structure, and brain function of older adults.
Detailed Description
Recent studies have shown the encouraging effects of fitness training on human cognition, and brain structure and function. Such effects are of great interest both for what may they tell us about the ...
Eligibility Criteria
Inclusion
- 60 to 75 years of age (for Sedentary Older Adults)
- Sedentary Older Adults: no physical activity in last six months; Young Comparison Sample: Moderately active lifestyle
- Capable of performing exercise
- Personal physician's examination and consent to participate in testing and exercise or control intervention
- Successful completion of graded exercise test without evidence of cardiac abnormalities or responses
- Adequate performance on the Pfeiffer (1979) Mental Status measure - Corrected (near and far) vision 20/40 or better
- Right-handed
- Intention to remain in the local area over the study period
Exclusion
- Sedentary Older Adults: self reported physical activity on regular basis (2 times or more per week) in last six months; Young Comparison Sample: sedentary or highly active/athletic lifestyle
- Any physical disability that prohibits mobility (walking), stretching etc.
- Depression score on GDS indicative of clinical depression
- Presence of any implanted devices such as cardiac pacemakers or autodefibrillators; neural pacemakers, aneurysm clips in the CNS; cochlear implants; metallic bodies in the eye or CNS; any form of wires or metal devices that concentrate radiofrequency fields
- Left-handed
- Individuals with chronic inflammation (e.g. severe arthritis, psoriasis, inflammatory bowel disease, asthma, polyneuropathies, Lupus)
- Intent to move or take an extended vacation (i.e. longer than 1 month during the study period)
Key Trial Info
Start Date :
April 1 2006
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
May 1 2012
Estimated Enrollment :
179 Patients enrolled
Trial Details
Trial ID
NCT00438347
Start Date
April 1 2006
End Date
May 1 2012
Last Update
November 8 2016
Active Locations (2)
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1
Beckman Institute, University of Illinois
Champaign, Illinois, United States, 61801
2
University of Illinois
Urbana, Illinois, United States, 61801