Status:

TERMINATED

Efficacy and Safety of AVE1625 as a Co-treatment With Antipsychotic Therapy in Schizophrenia

Lead Sponsor:

Sanofi

Conditions:

Schizophrenia

Eligibility:

All Genders

18-65 years

Phase:

PHASE2

Brief Summary

AVE1625 is a new potent and selective cannabinoid 1 (CB1) antagonist in clinical development for the treatment of cognitive impairment in patients diagnosed with schizophrenia. The main objective of ...

Eligibility Criteria

Inclusion

  • Outpatients with diagnosis of schizophrenia (diagnosed ≤ 35 years of age).
  • Current treatment consisting exclusively of olanzapine, risperidone/paliperidone, quetiapine or aripiprazole monotherapy for at least 2 months.

Exclusion

  • Inpatient hospitalization within past 3 months.
  • Residence at the current address \< 3 months due to any instability in the disease.
  • Presence of depressive symptoms.
  • Past history of clinically significant violent behavior.
  • Substance dependence or abuse.
  • Pregnant or breast-feeding women or women not protected by effective contraceptive method of birth control.
  • The investigator will evaluate whether there are other reasons why a patient may not participate.

Key Trial Info

Start Date :

February 1 2007

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

September 1 2009

Estimated Enrollment :

873 Patients enrolled

Trial Details

Trial ID

NCT00439634

Start Date

February 1 2007

End Date

September 1 2009

Last Update

May 18 2016

Active Locations (2)

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Page 1 of 1 (2 locations)

1

Sanofi-Aventis Administrative Office

Bridgewater, New Jersey, United States, 08807

2

Sanofi-Aventis Administrative Office

Laval, Canada