Status:

TERMINATED

Monotherapy Versus Placebo Over 14 or 17 Days in Healthy and Hepatitis C Infected Adults

Lead Sponsor:

GlaxoSmithKline

Conditions:

Hepatitis C, Chronic

Hepatitis C

Eligibility:

All Genders

18-55 years

Phase:

PHASE1

Brief Summary

This study represents the first administration of GSK625433 in humans. The study is designed to evaluate initial safety and tolerability in healthy adults as well as anti-viral activity in Hepatitis C...

Eligibility Criteria

Inclusion

  • Inclusion criteria:
  • Healthy males \& females
  • Part 1 ages 18-60
  • Part 2 ages 18-50 \& 65-80
  • Within normal weight range given your height
  • Negative urine drug and alcohol test
  • Willing to follow all study procedures
  • Exclusion criteria:
  • Any significant abnormal lab, ECG, medical or physical exam finding during screening
  • Allergy to the study drug
  • Excessive alcohol intake
  • Positive HIV or hepatitis B or C result
  • Use of prescription or non-prescription drugs within one week of study start except for birth control
  • Blood pressure meds \& Tylenol
  • Pregnant or lactating women

Exclusion

    Key Trial Info

    Start Date :

    October 1 2006

    Trial Type :

    INTERVENTIONAL

    Allocation :

    ACTUAL

    End Date :

    March 1 2007

    Estimated Enrollment :

    48 Patients enrolled

    Trial Details

    Trial ID

    NCT00439959

    Start Date

    October 1 2006

    End Date

    March 1 2007

    Last Update

    June 4 2012

    Active Locations (1)

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    Page 1 of 1 (1 locations)

    1

    GSK Investigational Site

    Evansville, Indiana, United States, 47714