Status:
COMPLETED
The Effect Of A Controlled Daily Skin Care Regimen On Retinoic Acid Tolerance
Lead Sponsor:
University of Michigan
Collaborating Sponsors:
Unilever R&D
Conditions:
Sun-Damaged Skin
Retinoid Intolerance
Eligibility:
All Genders
40-90 years
Phase:
NA
Brief Summary
Sun-damaged skin, caused by chronic exposure to ultraviolet (UV) light, is characterized by features such as wrinkling, uneven skin color, roughness and brown spots. An effective treatment for sun-dam...
Detailed Description
Sun-damaged skin, caused by chronic exposure to ultraviolet (UV) light, is characterized by features such as wrinkling, uneven skin color, roughness and brown spots. An effective treatment for sun-dam...
Eligibility Criteria
Inclusion
- Caucasians between the ages of 40 and 90 with moderate to severe sun-damage on the face who are generally healthy may participate.
- You must demonstrate a previous history of retinoid intolerance (established through prior history and the 2-week retinoid treatment phase of this study).
- Women of childbearing potential must agree to use an accepted form of birth control for the entire duration of the study.
- You must live within a reasonable driving distance of Ann Arbor, Michigan, and/or be able to attend all of the scheduled appointments during the study.
Exclusion
- You may not have used any topical or systemic retinoids in the past 6 months.
- Women who are pregnant or nursing may not participate.
- If you have a history of non-melanoma skin cancer on the face in the past 5 years, you may not participate.
- If you have any history of malignant melanoma you may not participate.
- If you have any other skin condition or facial hair that will interfere with the study evaluations, you may not participate.
- If you have a known sensitivity to any of the ingredients in the study cream or Dove products, you may not participate.
- If you are currently on special daily skin care regimens that include cleansing with Dove, Olay, Aveeno or Cetaphil liquid facial cleansers and using facial moisturizers more than twice a day you may not participate.
Key Trial Info
Start Date :
February 1 2007
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
November 1 2009
Estimated Enrollment :
40 Patients enrolled
Trial Details
Trial ID
NCT00440024
Start Date
February 1 2007
End Date
November 1 2009
Last Update
March 13 2020
Active Locations (1)
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1
University of Michigan Department of Dermatology
Ann Arbor, Michigan, United States, 48109