Status:
UNKNOWN
Comparison of Efficacy of Two Groups of Glaucoma Drops (Xalatan vs.Cosopt) in Reducing Eye Pressure Following Laser (SLT)Treatment in the Management of Glaucoma.
Lead Sponsor:
Advanced Glaucoma Specialists
Collaborating Sponsors:
Merck Sharp & Dohme LLC
Conditions:
Open Angle Glaucoma
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
WHAT IS THIS STUDY ABOUT? Glaucoma and ocular hypertension are chronic eye diseases that can damage the optic nerve and lead to vision loss or blindness. The optic nerve acts like an electric cable wi...
Detailed Description
Introduction Selective Laser Trabeculoplasty has been shown as a relatively safe and effective treatment modality for lowering IOP in various forms of open-angle glaucoma (Latina et al). It lowers IOP...
Eligibility Criteria
Inclusion
- Adult subjects of either sex, of any race, eighteen years of age or older.
- Diagnosis: Primary Open Angle Glaucoma, Pseudoexfoliation Glaucoma, Ocular Hypertension.
- Mild to moderate glaucoma only: Pattern standard deviation (PSD); more than 1DB and less than 6 DB on Humphrey Visual Field.
- Subject may be:
- A newly diagnosed glaucoma or
- A pre-existing glaucoma on not more than two topical antiglaucoma medications.
- On no systemic medications known to increase IOP (e.g. steroids)
- Visual acuity equal or better than 20/200 in the study eye
- IOP less than 35 mm Hg in the study eye
- No previous intraocular surgery within last 6 months, except laser PI greater than 3 months ago.
Exclusion
- Pigmentary OAG,
- Proliferative diabetic retinopathy,
- History of chronic or recurrent severe inflammatory eye disease (i.e. scleritis, uveitis, herpes keratitis),
- Known allergy to COSOPT or any of Prostaglandin Analogues,
- Chronic Obstructive Airways Disease (COPD),
- Sinus bradycardia (heart rate \< 60 beats per minute),
- Second or third-degree atrioventricular block,
- Overt cardiac failure.
- Pregnant and nursing mothers.
Key Trial Info
Start Date :
October 1 2006
Trial Type :
INTERVENTIONAL
End Date :
Estimated Enrollment :
30 Patients enrolled
Trial Details
Trial ID
NCT00440336
Start Date
October 1 2006
Last Update
March 1 2007
Active Locations (1)
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1
Advanced Glaucoma Specialist
Reading, Massachusetts, United States, 01867