Status:
COMPLETED
Safety And Efficacy Of Solifenacin In Men With Overactive Bladder (OAB) And Detrusor Underactivity
Lead Sponsor:
University of L'Aquila
Conditions:
Overactive Bladder
Detrusor Underactivity
Eligibility:
MALE
40-80 years
Brief Summary
Detrusor underactivity (DUA) in men is responsible for LUTS in a significant minority, the symptoms being indistinguishable from those seen in BOO. The International Continence Society (ICS) defines D...
Eligibility Criteria
Inclusion
- Men aged \> 40 years were eligible if by 7-day bladder diary they had urinary frequency (8 or more micturitions per 24 hours) and urgency, with or without urgency incontinence (1 or more episodes per 24 hours) together with coexistence low detrusor contractility.
Exclusion
- Urinary tract infection,
- Bladder stone, urogenital tumors,
- Prostate surgery,
- Use of indwelling catheter or self-catheterization program,
- Medications that could affect the lower urinary tract function,
- History of neurological disease,
- Acute urinary retention or any condition for which antimuscarinic was contraindicated.
- Antimuscarinic, antispasmodic, or electrostimulation within 1 month;
- Any investigational drug within 2 months; or
- A 5a-reductase inhibitor within 3 months of screening.
Key Trial Info
Start Date :
February 1 2006
Trial Type :
OBSERVATIONAL
End Date :
Estimated Enrollment :
Patients enrolled
Trial Details
Trial ID
NCT00441428
Start Date
February 1 2006
Last Update
June 4 2008
Active Locations (1)
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1
University of L'Aquila
L’Aquila, Abruzzo, Italy, 67100