Status:

COMPLETED

Sub-Tenon Triamcinolone in the Prevention of Radiation-Induced Macular Edema

Lead Sponsor:

Wills Eye

Conditions:

Melanoma

Eligibility:

All Genders

18+ years

Phase:

NA

Brief Summary

Melanoma is the most common primary tumour which occurs inside the eye. For over 20-years, it has been possible, in many cases, to use local delivery of radiation to the eye to treat this type of tumo...

Detailed Description

BACKGROUND: Uveal melanoma is the most common primary intraocular malignancy. Plaque radiation (brachytherapy) has emerged as the most common treatment in the current management of uveal melanoma, but...

Eligibility Criteria

Inclusion

  • Uveal melanoma new diagnosis, undergoing plaque radiation treatment

Exclusion

  • Pre-existing macular disease
  • age-related macular degeneration
  • diabetic maculopathy
  • pre-existing retinal vascular occlusion
  • macular hole
  • surface wrinkling retinopathy
  • prior retinal detachment
  • media opacities precluding accurate OCT imaging
  • known 'steroid responder'
  • glaucoma

Key Trial Info

Start Date :

November 1 2004

Trial Type :

INTERVENTIONAL

End Date :

May 1 2007

Estimated Enrollment :

170 Patients enrolled

Trial Details

Trial ID

NCT00441662

Start Date

November 1 2004

End Date

May 1 2007

Last Update

March 1 2007

Active Locations (1)

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1

Ocular Oncology Service, Wills Eye Institute

Philadelphia, Pennsylvania, United States, 19107