Status:

COMPLETED

A Placebo-controlled Study to Investigate the Safety, and Pharmacokinetics of Oral GSK626616AC in Healthy Subjects

Lead Sponsor:

GlaxoSmithKline

Conditions:

Healthy Subjects

Anaemia

Eligibility:

All Genders

18-55 years

Phase:

PHASE1

Brief Summary

This is a first time in human study to investigate the safety of GSK626616AC given as oral single and repeat doses in healthy subjects. An additional group of subjects will be assessed to determine th...

Eligibility Criteria

Inclusion

  • Age 18 to 55 years healthy subjects
  • Hemoglobin values of 13.5-17.0 g/dL for males or 12.0-15.5 g/dL for females.
  • Females cannot be pregnant.

Exclusion

  • Cannot have exposure to greater than 4 new chemical entities within 12 months.
  • Cannot have a clinical history of current alcohol, or illicit drug use which, in the judgment of the Investigator, would interfere with the subject's ability to comply with the dosing schedule.
  • Cannot have a history of regular use of tobacco- or nicotine-containing products within 3 months.
  • Must not have received a blood transfusion or had a donation of blood within 3 months prior to study entry.
  • Cannot use be taking prescription, non-prescription or illicit drugs.

Key Trial Info

Start Date :

November 1 2006

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

Estimated Enrollment :

90 Patients enrolled

Trial Details

Trial ID

NCT00443170

Start Date

November 1 2006

Last Update

March 19 2012

Active Locations (3)

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Page 1 of 1 (3 locations)

1

GSK Investigational Site

Randwick, Sydney, New South Wales, Australia, 2031

2

GSK Investigational Site

Herston, Queensland, Australia, 4006

3

GSK Investigational Site

Adelaide, South Australia, Australia, 5000