Status:

COMPLETED

A Study of the Safety of Rituxan in Patients With Rheumatoid Arthritis After an Inadequate Response to Previous Anti-TNF Therapy (SUNSTONE)

Lead Sponsor:

Genentech, Inc.

Collaborating Sponsors:

Biogen

Conditions:

Rheumatoid Arthritis

Eligibility:

All Genders

18+ years

Brief Summary

This is an observational study designed to follow patients with RA who have had an inadequate response to one or more anti-TNF therapies and who will receive Rituxan. Approximately 1000 patients in th...

Eligibility Criteria

Inclusion

  • No prior use of Rituxan (except if received within 8 weeks of screening)
  • Signed Informed Consent Form
  • Age ≥ 18 years
  • Diagnosis of RA
  • Inadequate response to one or more anti-TNF therapies

Exclusion

  • Have known hypersensitivity to any component of a humanized or murine monoclonal antibody

Key Trial Info

Start Date :

January 1 2007

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

September 1 2013

Estimated Enrollment :

1026 Patients enrolled

Trial Details

Trial ID

NCT00443443

Start Date

January 1 2007

End Date

September 1 2013

Last Update

March 30 2015

Active Locations (193)

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Page 1 of 49 (193 locations)

1

Rheumatology Associates, PC

Birmingham, Alabama, United States, 35205

2

Rheumatology Associates of N. AL, P.C.

Huntsville, Alabama, United States, 35801

3

Clinic for Rheumatic Diseases - Research Department

Tuscaloosa, Alabama, United States, 35406

4

Arizona Arthritis and Rheumatology Research, PLLC

Paradise Valley, Arizona, United States, 85253

A Study of the Safety of Rituxan in Patients With Rheumatoid Arthritis After an Inadequate Response to Previous Anti-TNF Therapy (SUNSTONE) | DecenTrialz