Status:
COMPLETED
Clopidogrel Reloading in Clopidogrel Resistant Patients With ACS
Lead Sponsor:
Sheba Medical Center
Conditions:
Clopidogrel Non-Responsiveness
Eligibility:
All Genders
18-80 years
Phase:
PHASE3
Brief Summary
Laboratory clopidogrel resistance is associated with adverse atherothrombotic events in patients with coronary artery disease. In the proposed study we wish to prospectively assess the effect of reloa...
Detailed Description
Prior studies have demonstrated significant variability in platelet response to clopidogrel in patients with coronary artery disease (CAD). Up to 25% of patients have been shown to be non-responders t...
Eligibility Criteria
Inclusion
- age equal or over 18 years
- acute coronary syndrome
- Clopidogrel non-responsive
- signed an informed consent
Exclusion
- Bleeding disorder
- hypersensitivity to aspirin or clopidogrel
- any contraindication to anti-thrombotic or anticoagulant therapy
- active neoplastic disorder
Key Trial Info
Start Date :
March 1 2005
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
June 1 2007
Estimated Enrollment :
50 Patients enrolled
Trial Details
Trial ID
NCT00444132
Start Date
March 1 2005
End Date
June 1 2007
Last Update
September 20 2007
Active Locations (1)
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1
ICCU, Sheba Medical Center
Tel-hashomer, Ramat Gan, Israel