Status:
UNKNOWN
Ureteropelvic Junction Obstruction in Early Childhood: Comparison of Surgical Therapy and Surveillance. A Prospective, Randomized, Controlled Multi-Center Study
Lead Sponsor:
University Hospital, Essen
Conditions:
Unilateral Ureteropelvic Junction Obstruction
Eligibility:
All Genders
4-6 years
Phase:
NA
Brief Summary
In this randomized trial surgical therapy and surveillance of ureteropelvic junction obstruction will be compared, regarding partial renal function.
Eligibility Criteria
Inclusion
- unilateral ureteropelvic junction obstruction
- diameter of renal pelvis greater 12 mm
- partial renal function of 35%-55% proofed by scintigraphy
- urodynamically relevant decrease in renal drainage proofed by diuresis scintigraphy at the age of 4 weeks up to 6 months
- Abscence of clinical symptoms
- Healthy contralateral kidney
Exclusion
- Global decrease in renal function
- renal dystopia
- megaureter
- vesico-ureteral reflux
- progressive hydronephrosis
- oligohydrammnion
- voiding dysfunction
- bilateral hydronephrosis
- severe chronical illness
- decrease of partial renal function of more then 5% during allocation
Key Trial Info
Start Date :
March 1 2007
Trial Type :
INTERVENTIONAL
End Date :
Estimated Enrollment :
240 Patients enrolled
Trial Details
Trial ID
NCT00444431
Start Date
March 1 2007
Last Update
March 7 2007
Active Locations (2)
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1
University Hospital of Essen, Department of Pediatric Nephrology
Essen, North Rhine-Westphalia, Germany, 45122
2
University Hospital of Essen, Department of Urology
Essen, North Rhine-Westphalia, Germany, 45122