Status:

COMPLETED

Symptomatic Efficacy of Diacerein in Knee Osteoarthritis

Lead Sponsor:

Laboratoires NEGMA

Conditions:

Knee Osteoarthritis

Eligibility:

All Genders

18+ years

Phase:

PHASE4

Brief Summary

Pain is the main symptom of osteoarthritis that motivates medical visits. Diacerhein has already demonstrated its efficacy in knee and/or hip osteoarthritis. This study aims at confirming the efficacy...

Eligibility Criteria

Inclusion

  • Painful primary osteoarthritis (VAS ≥ 40 mm)
  • Radiologically proven (Kellgren \& Lawrence grade I to III)
  • Requiring the prescription of a symptomatic treatment of pain

Exclusion

  • Severe associated diseases
  • Wash-out: AINS, Coxibs, Paracetamol, anti-osteoarthritic treatments, hyaluronic acid, knee tidal lavage
  • Other osteoarticular disease

Key Trial Info

Start Date :

November 1 2005

Trial Type :

INTERVENTIONAL

End Date :

September 1 2006

Estimated Enrollment :

500 Patients enrolled

Trial Details

Trial ID

NCT00445276

Start Date

November 1 2005

End Date

September 1 2006

Last Update

March 4 2010

Active Locations (1)

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Chu Trousseau

Tours, France, 37044