Status:

COMPLETED

Risk Factors for Barrett's Esophagus in Patients With BE, Gastroesophageal Reflux, or Gastrointestinal Bleeding

Lead Sponsor:

Massachusetts General Hospital

Collaborating Sponsors:

National Cancer Institute (NCI)

Conditions:

Precancerous Condition

Eligibility:

All Genders

18-90 years

Brief Summary

RATIONALE: A study that evaluates DNA changes and other disease-related health information in patients with Barrett's esophagus, gastroesophageal reflux, or gastrointestinal bleeding may help doctors ...

Detailed Description

OBJECTIVES: * Assess the role of several genetically determined factors that, in combination with CagA status, cigarette smoking, alcohol, and diet to varying degrees, result in an increased risk for...

Eligibility Criteria

Inclusion

  • DISEASE CHARACTERISTICS:
  • Undergoing elective esophagogastroduodenoscopy for any of the following reasons:
  • Surveillance of Barrett's esophagus
  • Evaluation of severe or refractory gastroesophageal reflux disease or chest pain thought to be due to reflux
  • Gastrointestinal bleeding
  • PATIENT CHARACTERISTICS:
  • Not pregnant
  • PRIOR CONCURRENT THERAPY:
  • Not specified

Exclusion

    Key Trial Info

    Start Date :

    August 1 2005

    Trial Type :

    OBSERVATIONAL

    Allocation :

    ACTUAL

    End Date :

    March 1 2013

    Estimated Enrollment :

    170 Patients enrolled

    Trial Details

    Trial ID

    NCT00445653

    Start Date

    August 1 2005

    End Date

    March 1 2013

    Last Update

    January 18 2017

    Active Locations (2)

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    Page 1 of 1 (2 locations)

    1

    Massachusetts General Hospital Cancer Center

    Boston, Massachusetts, United States, 02114

    2

    Harvard School of Public Health

    Boston, Massachusetts, United States, 02115