Status:

TERMINATED

The Effects of Ibandronate or Teriparatide Therapy on Bone Histology and Biochemical Indices in Patients on Hemodialysis With Low Bone Mineral Density

Lead Sponsor:

Papageorgiou General Hospital

Conditions:

Osteoporosis

Eligibility:

All Genders

18+ years

Phase:

PHASE4

Brief Summary

Hemodialysis patients with low bone density (total hip T-score \<-2.5) will be assigned to receive teriparatide (those with histologic confirmation of adynamic bone disease) or ibandronate (subjects w...

Eligibility Criteria

Inclusion

  • Bone mineral density (T-score\<-2.5)
  • Adynamic bone disease for the teriparatide group
  • Increased osteoclast number on bone biopsy (high turnover) for the ibandronate group
  • Calcium greater than 8.1 mg/dl

Exclusion

  • Suspected carcinoma
  • Unstable clinical setting

Key Trial Info

Start Date :

July 1 2006

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

Estimated Enrollment :

19 Patients enrolled

Trial Details

Trial ID

NCT00446589

Start Date

July 1 2006

Last Update

October 29 2014

Active Locations (1)

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1

Papageorgiou General Hospital

Thessaloniki, Greece, 56403