Status:

COMPLETED

Clinical Investigation to Evaluate Safety and Performance of the EndoFast Reliant™ System in Vaginal Wall Reinforcement

Lead Sponsor:

Endogun Medical Systems Ltd.

Conditions:

Pelvic Organ Prolapse

Eligibility:

FEMALE

40-80 years

Phase:

NA

Brief Summary

The purpose of this study is to clinically assess the safety and performance of the EndoFast Reliant™ system as a less invasive treatment for Pelvic Organ Prolapse.

Detailed Description

Background: Pelvic Organ Prolapse represents a significant problem worldwide and may have a significant negative impact on a woman's quality of life. The uterus, rectum and the bladder are held in th...

Eligibility Criteria

Inclusion

  • Female aged between 40-80 years (inclusive) who is not pregnant or planning to have further births.
  • Subject suffers from Pelvic Organ Prolapse confirmed by vaginal inspection.
  • Patient under reliable form of contraceptive measure or menopausal.
  • Subject able to comprehend procedure and has signed Informed Consent Form for participation in this study.
  • Subject able to complete the applicable questionnaires.

Exclusion

  • Planned to undergo hysterectomy.
  • Uterine prolapse equal to or greater than 3rd degree.
  • Documented Stress Urinary Incontinence on physical examination with full bladder or during complete urodynamic assessment with and without prolapse reduction.
  • Any chronic active and uncontrolled disease.
  • Vaginal bleeding disorders.
  • Needing emergency surgery.
  • Any acute disease.
  • Blood clotting disorders and/or anticoagulant treatment.
  • Known cognitive or psychiatric disorder.
  • High operative risk.
  • Any ongoing malignant disease.
  • Concurrent participation in any other clinical trial

Key Trial Info

Start Date :

February 1 2007

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

June 1 2009

Estimated Enrollment :

20 Patients enrolled

Trial Details

Trial ID

NCT00446693

Start Date

February 1 2007

End Date

June 1 2009

Last Update

November 19 2009

Active Locations (3)

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Page 1 of 1 (3 locations)

1

CHU de Caen

Caen, France, 14033

2

Hôpital Jeanne de Flandre - CHRU Gynécologie obstétrique

Lille, France, 56037

3

Sheba Medical Center

Ramat Gan, Israel, 52621