Status:
COMPLETED
Estimation of Intrinsic Positive End-Expiratory Pressure (PEEP) in Acute Respiratory Distress Syndrome (ARDS)
Lead Sponsor:
Texas Tech University Health Sciences Center, El Paso
Conditions:
Acute Respiratory Distress Syndrome
Eligibility:
All Genders
18+ years
Brief Summary
ARDS (Acute Respiratory Distress Syndrome) is a condition of severe inflammation and excess fluids in the lungs that impairs their function of oxygen uptake to the point of needing a ventilator (breat...
Detailed Description
Intrinsic PEEP (Positive-End Expiratory Pressure) was measured by end-expiratory occlusion method and estimated using formulas derived from measured expiratory flows and a postulated linear pressure-f...
Eligibility Criteria
Inclusion
- Patients 18 years of age or older with diagnosis of ARDS, as defined by the American- European Consensus Conference 4
- Receiving mechanical ventilation.
- Presence of autoPEEP by inspection of flow-time waveforms displayed by the mechanical ventilator.
Exclusion
- Known or suspected diagnosis of COPD or airflow limitation.
- Next of kin not available to consent.
- Contraindication to receive a muscle relaxant when measurements may be inaccurate without its administration.
- Pregnancy
Key Trial Info
Start Date :
January 1 2004
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
April 1 2007
Estimated Enrollment :
6 Patients enrolled
Trial Details
Trial ID
NCT00446706
Start Date
January 1 2004
End Date
April 1 2007
Last Update
May 9 2017
Active Locations (1)
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1
Thomason Hospital (Now University Medical Center)
El Paso, Texas, United States, 79905