Status:

COMPLETED

A Study of Encapsulated Cell Technology (ECT) Implant for Participants With Early Stage Retinitis Pigmentosa

Lead Sponsor:

Neurotech Pharmaceuticals

Conditions:

Retinitis Pigmentosa

Eligibility:

All Genders

18-64 years

Phase:

PHASE2

Brief Summary

The purpose of this study is to look at the safety and effectiveness of CNTF implants on vision in persons with retinitis pigmentosa, Usher type II \& III, and Choroideremia. This research is being do...

Detailed Description

This study will involve about 18 visits over 2½ years for specific tests of the participant's vision and health. These visits may include visual exams, blood draw for laboratory testing, brief medical...

Eligibility Criteria

Inclusion

  • Study inclusion / exclusion criteria:
  • Criteria for patients to qualify for the study include, but are not limited to:
  • Over 18 years of age, and less than 65 years of age
  • Diagnosis of retinitis pigmentosa, Usher Syndrome Type 2 or 3 or Choroideremia
  • Visual acuity no worse than 20/63
  • Experience with at least two full threshold Humphrey Visual Field 30-2 tests, one completed within the year prior to enrolling in this study
  • The following criteria will exclude patients from the study:
  • Pregnant or lactating females, or females planning to become pregnant during the study or not using an acceptable method of contraception.
  • Retinitis pigmentosa caused by a classic syndrome, including Usher Type I
  • Other eye diseases including advanced cataract.
  • Chronic systemic disease requiring continuous treatment with systemic steroids, immunosuppressive medications or insulin.

Exclusion

    Key Trial Info

    Start Date :

    January 22 2007

    Trial Type :

    INTERVENTIONAL

    Allocation :

    ACTUAL

    End Date :

    April 19 2010

    Estimated Enrollment :

    73 Patients enrolled

    Trial Details

    Trial ID

    NCT00447980

    Start Date

    January 22 2007

    End Date

    April 19 2010

    Last Update

    May 1 2025

    Active Locations (12)

    Enter a location and click search to find clinical trials sorted by distance.

    Page 1 of 3 (12 locations)

    1

    Retina-Vitreous Associates Medical Group

    Beverly Hills, California, United States, 90211

    2

    University of Califoria, Davis

    Sacramento, California, United States, 95817

    3

    University of California, San Francisco

    San Francisco, California, United States, 94143-0730

    4

    Bascom Palmer Eye Insitute

    Miami, Florida, United States, 33101

    A Study of Encapsulated Cell Technology (ECT) Implant for Participants With Early Stage Retinitis Pigmentosa | DecenTrialz