Status:
SUSPENDED
The Chinese Mutation Hotspot of ENaC Causing Liddle's Syndrome and the Association of ENaC Variations and Hypertension
Lead Sponsor:
Peking Union Medical College
Conditions:
Hypertension
Eligibility:
All Genders
8-70 years
Brief Summary
The variations of ENaC have an impact on the degradation of epithelial sodium channels and sodium reabsorption, and thus are associated with hypertension and hypokalemia. Liddle's syndrome is a rare ...
Eligibility Criteria
Inclusion
- Clinical diagnosis of hypertension and Liddle's syndrome
- Clinical diagnosis of normal controls with no cardiovascular disease
Exclusion
- Hypertension caused by other single gene mutation
Key Trial Info
Start Date :
May 1 2005
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
December 1 2009
Estimated Enrollment :
2000 Patients enrolled
Trial Details
Trial ID
NCT00448162
Start Date
May 1 2005
End Date
December 1 2009
Last Update
March 31 2011
Active Locations (1)
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1
FuWai Hospital
Beijing, Beijing Municipality, China, 100037