Status:
UNKNOWN
Novel Pharmacotherapy for Dual Dependence
Lead Sponsor:
Bankole Johnson
Collaborating Sponsors:
National Institute on Drug Abuse (NIDA)
Conditions:
Alcohol Dependence
Cocaine Dependence
Eligibility:
All Genders
18+ years
Phase:
PHASE3
Brief Summary
The purpose of this study is to evaluate the effects of Topiramate and Cognitive Behavioral Therapy for the treatment of alcohol and cocaine dependence.
Detailed Description
Our objective is to understand the basic mechanisms that underpin substance dependence, and to develop efficacious treatments for individuals with comorbid cocaine and alcohol dependence. Participant...
Eligibility Criteria
Inclusion
- Subjects will be men and women between the ages of 18 years and older.
- Must meet at least three of the seven DSM IV diagnostic criteria for alcohol and cocaine dependence.
- Express a desire for treatment.
- Literacy in English and ability to read, understand, and complete the ratings scales and questionnaires accurately, follow instructions, and make use of the behavioral treatments are required.
- Prospective subjects must report cocaine use of at least once per month and alcohol consumption of ≥21 drinks/week and ≥14 drinks/week for men and women respectively, during the past 30 days
- At least one positive urine drug screen for cocaine at screen or baseline prior to randomization.
Exclusion
- Please contact site for additional information
Key Trial Info
Start Date :
March 1 2007
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
June 1 2013
Estimated Enrollment :
180 Patients enrolled
Trial Details
Trial ID
NCT00448825
Start Date
March 1 2007
End Date
June 1 2013
Last Update
March 15 2013
Active Locations (2)
Enter a location and click search to find clinical trials sorted by distance.
1
University of Virginia Center for Addiction Research and Education
Charlottesville, Virginia, United States, 22911
2
University of Virginia Center for Addiction Research and Education
Richmond, Virginia, United States, 23294