Status:

COMPLETED

Ologen (OculusGen)-Glaucoma Case Control Trial in India

Lead Sponsor:

Pro Top & Mediking Company Limited

Conditions:

Glaucoma

Eligibility:

All Genders

30+ years

Phase:

PHASE3

Brief Summary

The purpose of this study is to compare the safety and effectiveness of trabeculectomy with ologen (OculusGen) Biodegradable Collagen Matrix Implant and trabeculectomy without antifibrotic agents.

Detailed Description

1. Study Objective: To determine the safety and effectiveness of the ologen (OculusGen) Biodegradable Collagen Matrix Implant in filtration surgery. The primary endpoint is to prove the effectiveness ...

Eligibility Criteria

Inclusion

  • Age 30 years or over.
  • No previous intraocular operative surgery
  • Uncontrolled glaucoma, with failed medical and laser treatment, requiring trabeculectomy.
  • Subject able and willing to cooperate with investigation plan.
  • Subject able and willing to complete postoperative follow-up requirements.
  • Subject willing to sign informed consent form.

Exclusion

  • Known allergic reaction to porcine collagen.
  • Subject is on warfarin and discontinuation is not recommended.
  • Patient who has been diagnosed for one of following glaucoma: normal tension glaucoma, uveitic glaucoma, aphakia or pseudophakia glaucoma, neovascular glaucoma and other classified secondary glaucoma.
  • Participation in an investigational study during the 30 days proceeding trabeculectomy.
  • Ocular infection within 14 days prior to trabeculectomy.
  • Pregnant or breast-feeding women

Key Trial Info

Start Date :

January 1 2007

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

October 1 2011

Estimated Enrollment :

40 Patients enrolled

Trial Details

Trial ID

NCT00448929

Start Date

January 1 2007

End Date

October 1 2011

Last Update

June 27 2017

Active Locations (1)

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L. V. Prasad Eye Institute

Hyderabad, Andhra Pradesh, India, 500 034