Status:

COMPLETED

The Utility of Ischemia Modified Albumin (IMA) in Sepsis

Lead Sponsor:

Inverness Medical Innovations

Conditions:

Sepsis

Severe Sepsis

Eligibility:

All Genders

18+ years

Brief Summary

The purpose of this study is to determine if levels of ischemia modified albumin (IMA) in blood are elevated in patients with suspected infection and are predictive of severity of illness in patients ...

Detailed Description

Sepsis is an unconquered challenge in medicine, affecting people of all ages and demographics. Severe sepsis affects approximately 751,000 patients in the United States per annum, with healthcare cost...

Eligibility Criteria

Inclusion

  • Inclusion Criteria for Sepsis Subjects:
  • 18 years of age or older
  • Able to provide informed consent
  • Clinical suspicion of infection
  • Exclusion Criteria for Sepsis Subjects:
  • Active chest pain of suspected cardiac origin
  • ST elevation myocardial infarction or dynamic ST changes on EKG
  • Pregnant women
  • Cocaine use
  • Liver disease
  • Unable to speak or understand the English language
  • Inclusion Criteria for Control Subjects:
  • 18 years of age or older
  • Emergency Department presentation as a result of a non-infectious etiology as determined by the treating clinicians
  • Able to provide informed consent
  • Exclusion Criteria for Control Subjects:
  • Suspected Infection
  • Temperature \>100.4°F
  • Pregnant women
  • Possible cardiac, intestinal or cerebral ischemia
  • Liver disease
  • Any source of inflammation as part of their presentation
  • cancer, any type

Exclusion

    Key Trial Info

    Start Date :

    March 1 2007

    Trial Type :

    OBSERVATIONAL

    Allocation :

    ACTUAL

    End Date :

    September 1 2007

    Estimated Enrollment :

    150 Patients enrolled

    Trial Details

    Trial ID

    NCT00448968

    Start Date

    March 1 2007

    End Date

    September 1 2007

    Last Update

    September 27 2007

    Active Locations (3)

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    Page 1 of 1 (3 locations)

    1

    Beth Israel Deaconess Medical Center

    Boston, Massachusetts, United States, 02215

    2

    Cleveland Clinc

    Cleveland, Ohio, United States, 44195

    3

    University of Pennsylvania School of Medicine

    Philadelphia, Pennsylvania, United States, 19104