Status:

UNKNOWN

Magnetic Resonance Imaging of Brain Development in Autism

Lead Sponsor:

UMC Utrecht

Conditions:

Autism

Eligibility:

All Genders

6-18 years

Brief Summary

The purpose of this study is to investigate brain development in autism by longitudinally assessing children with autism, as well as typically developing controls, using advanced MR techniques. We wil...

Eligibility Criteria

Inclusion

  • Aged 6 - 18 years at initial MRI
  • Inclusion criteria for subjects with autism
  • 1\) DSM-IV (APA, 1994) diagnosis of autism, according to ADI-R interview
  • Inclusion criteria for controls
  • no DSM-IV (APA, 1994) diagnosis, according to DISC interview
  • no scores in the clinical range on the Child Behavior Checklist (CBCL) and Teacher Rating Form (TRF)
  • IQ \> 70

Exclusion

  • major illness of the cardiovascular, the endocrine, the pulmonal or the gastrointestinal system
  • presence of metal objects in or around the body (pacemaker, dental braces)
  • history of or present neurological disorder
  • for individuals over 12 years of age: legal incompetence, defined as the obvious inability to comprehend the information that is presented by the investigator and is outlined in the Information letter and on which the decision to participate in the study is to be based

Key Trial Info

Start Date :

January 1 2006

Trial Type :

OBSERVATIONAL

End Date :

Estimated Enrollment :

300 Patients enrolled

Trial Details

Trial ID

NCT00449566

Start Date

January 1 2006

Last Update

March 20 2007

Active Locations (1)

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1

Dept. of Child and Adolescent Psychiatry, UMC Utrecht

Utrecht, Netherlands, 3584CX

Magnetic Resonance Imaging of Brain Development in Autism | DecenTrialz