Status:
COMPLETED
Multidrug Resistance After Trabeculectomy With Mitomycin C
Lead Sponsor:
University of Cologne
Conditions:
Glaucoma
Trabeculectomy
Eligibility:
All Genders
8-85 years
Brief Summary
We investigate whether mitomycin C treatment during previous filtration surgery induces P-glycoprotein expression.
Detailed Description
Despite the adjuvant use of mitomycin C during trabeculectomy, short-term and long-term failures still occur. We investigate whether mitomycin C treatment during previous trabeculectomy induces P-glyc...
Eligibility Criteria
Inclusion
- patients with planned trabeculectomy for elevated eye pressure
- one third of patients without previous trabeculectomy
- two thirds of patients with previous trabeculectomy (one third with and one third without the use of mitomycin C)
Exclusion
- patients not requiring surgery
- patients with planned surgery for elevated eye pressure other than trabeculectomy
Key Trial Info
Start Date :
Trial Type :
OBSERVATIONAL
End Date :
Estimated Enrollment :
30 Patients enrolled
Trial Details
Trial ID
NCT00449631
Last Update
March 26 2007
Active Locations (1)
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1
The University Hospital of Cologne
Cologne, Germany, 50924