Status:

COMPLETED

Neuropsychological and Neuroanatomical Studies of Young Children With and Without Type 1 Diabetes Mellitus

Lead Sponsor:

Stanford University

Collaborating Sponsors:

William E And Aenid R Weisgerber Foundation

Conditions:

Type 1 Diabetes Mellitus

Eligibility:

All Genders

3-10 years

Brief Summary

This study is being conducted to see if Type 1 diabetes mellitus has any affect on learning, behavior and development in young children and whether there are associated changes on their MRI scan.

Detailed Description

In this pilot study approximately 10-20 children between the ages of 3 to 10 years with Type 1 diabetes mellitus will have neuropsychological testing and a nonsedated MRI scan of the head performed ev...

Eligibility Criteria

Inclusion

  • Inclusion Criteria for study subjects:
  • To be between ages 3 to 10 years
  • Have been diagnosed with type 1 diabetes for at least 6 months; and
  • Do not have plans to move out of the area within the next 36 months.
  • Inclusion Criteria for control subjects:
  • To be between ages 3 to 10 years

Exclusion

  • No history of head trauma with any loss of consciousness,
  • Cystic fibrosis,
  • Prematurity (born less than 30 weeks of gestation),
  • Significant developmental delay (lack of single word speech or ability to walk independently by 18 months of age),
  • Neurologic disease independent of diabetes (eg seizure disorder); or
  • Medical contraindication to MRI procedure (eg metal appliances such as braces).

Key Trial Info

Start Date :

January 1 2007

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

March 1 2016

Estimated Enrollment :

30 Patients enrolled

Trial Details

Trial ID

NCT00449891

Start Date

January 1 2007

End Date

March 1 2016

Last Update

April 14 2016

Active Locations (1)

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Stanford University

Stanford, California, United States, 94305