Status:

UNKNOWN

Dendritic Cells in Patients Following Allogeneic Hematopoietic Stem Cell Transplantation

Lead Sponsor:

Technische Universität Dresden

Conditions:

Graft Versus Host Disease

Eligibility:

All Genders

18+ years

Brief Summary

We plan to investigate prospectively and simultaneously skin and blood DC subtypes, their donor/recipient origin and the correlation of DC reconstitution kinetics with treatment, clinical outcome and ...

Detailed Description

Blood and skin DC reconstitution shall be investigated in patients affected by hematological diseases and receiving HLA-matched, mobilized peripheral blood stem cells from related or unrelated donors....

Eligibility Criteria

Inclusion

  • Patient undergoing an allogeneic hematopoietic stem cell transplantation
  • Older than 18 years
  • WHO-Performance-Status 0 to3
  • Informed consent
  • Graft versus host disease of the skin

Exclusion

  • Clotting parameters more than double of normal
  • Infection of the skin
  • Leucocytes \< 1000/µl; Thrombocytes \< 20 000/µl

Key Trial Info

Start Date :

January 1 2005

Trial Type :

OBSERVATIONAL

End Date :

January 1 2010

Estimated Enrollment :

50 Patients enrolled

Trial Details

Trial ID

NCT00450268

Start Date

January 1 2005

End Date

January 1 2010

Last Update

March 22 2007

Active Locations (1)

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1

Universitätsklinik Carl Gustav Carus

Dresden, Germany, 01307