Status:

COMPLETED

Efficacy and Tolerability of Novel A2A Agonist in Treatment of Diabetic Neuropathic Pain

Lead Sponsor:

Swedish Orphan Biovitrum

Conditions:

Diabetic Neuropathic Pain

Eligibility:

All Genders

18+ years

Phase:

PHASE2

Brief Summary

The purpose of this study is to evaluate the efficacy and tolerability of BVT.115959 in diabetic patients with neuropathic pain who are either not on analgesia or are on stable analgesia in the month ...

Detailed Description

The planned study is an exploratory study which aims to provide proof of the efficacy of BVT.115959 in the reduction of the symptoms of pain. Thus, the primary objective is to evaluate the anticipated...

Eligibility Criteria

Inclusion

  • A diagnosis of type 1 or 2 diabetes mellitus and documented painful, symmetrical, sensorimotor polyneuropathy for at least 6 months
  • Either no analgesic medication or on stable analgesic medication for at least 4 weeks

Exclusion

  • Female patients who are fertile and of child-bearing potential
  • Clinically significant or unstable hepatic, respiratory, renal, hematologic, cardiovascular or peripheral vascular disease
  • Painful conditions that may confound the evaluation of neuropathic pain

Key Trial Info

Start Date :

May 1 2007

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

January 1 2008

Estimated Enrollment :

193 Patients enrolled

Trial Details

Trial ID

NCT00452777

Start Date

May 1 2007

End Date

January 1 2008

Last Update

November 3 2014

Active Locations (20)

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Page 1 of 5 (20 locations)

1

Biovitrum investigational site

České Budějovice, Czechia

2

Biovitrum investigational site

Litoměřice, Czechia

3

Biovitrum investigational site

Pilsen, Czechia

4

Biovitrum investigational site

Prague, Czechia