Status:

COMPLETED

Comparison of AC and PC Lenses After Vitreous Loss During ECCE

Lead Sponsor:

VA Office of Research and Development

Conditions:

Cataract

Eligibility:

All Genders

18+ years

Phase:

PHASE3

Brief Summary

Objective: The standard definition of failure in cataract surgery is best corrected visual acuity of less than 20/40 at one year. The specific aim of this cooperative study was to compare the failure ...

Detailed Description

Primary Hypothesis: There is no difference in failure rate between patients receiving anterior chamber or posterior chamber intraocular lenses following vitreous loss in extracapsular cataract extract...

Eligibility Criteria

Inclusion

  • The principal eligibility criterion was a visually significant lens opacity resulting in a best-corrected distance visual acuity of 20/50 or worse.

Exclusion

  • Age less than 18 years
  • Unwillingness to give informed consent
  • Unwillingness to agree to protocol follow-up
  • Visual acuity better than 20/50
  • Any other ocular disease which would preclude a final postoperative visual acuity of 20/40 or better (e.g., proliferative diabetic retinopathy, flaucoma, or Fuchs' dystrophy)
  • History of uveitis
  • Other contraindication to an IOL
  • Cataract attributable to trauma
  • Patient only had one eye with potential for useful vision
  • Any retinal thickening or definite hard exudates within one disk diameter of center of macula
  • Patient's other eye already entered into the study.
  • Patients could be screened for the study twice; once for each eye if they had a cataract in both. However, if the first procedure resulted in the patient being entered into the randomized study, the 5% NVP group, or the ICS group, then the second eye was not eligible for the study.

Key Trial Info

Start Date :

February 1 1992

Trial Type :

INTERVENTIONAL

End Date :

February 1 1998

Estimated Enrollment :

1202 Patients enrolled

Trial Details

Trial ID

NCT00453011

Start Date

February 1 1992

End Date

February 1 1998

Last Update

October 20 2015

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