Status:

WITHDRAWN

FHA: Characterization of Metabolic Status, Brain Circuitry, and Stress-Reactivity

Lead Sponsor:

Emory University

Conditions:

Anovulation

FHA

Eligibility:

FEMALE

18-35 years

Brief Summary

Functional Hypothalamic Amenorrhea (FHA), the spontaneous cessation of the menstrual cycle for at least 6 months after menstrual cyclicity has been established, is a common and reversible form of anov...

Eligibility Criteria

Inclusion

  • Inclusion criteria for participation are a gynecological age (age since menarche) \> 5 and \< 25 years, and chronological age \> 18 years, within 90-110% of ideal body weight as determined by the 1983 Metropolitan height and weight table for women, and exercise \< 10 h/wk and run \< 10 mi/wk, day-awake/night-asleep schedule.
  • Women in the FHA and PCOS groups have to fulfill the diagnostic criteria of FHA or PCOS and to have all other causes of amenorrhea and anovulation excluded.

Exclusion

  • Exclusion criteria are smoking, medications, including psychotropic or illicit drugs, medical, neurological, or ophthalmologic disease except acuity problems, a weight loss or gain of \> 10 lb within a year preceding or since the onset of amenorrhea, a major Axis I disorder other than depression, parturition in the last 12 months and/or lactating in the last 6 months.

Key Trial Info

Start Date :

July 1 2011

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

Estimated Enrollment :

Patients enrolled

Trial Details

Trial ID

NCT00453219

Start Date

July 1 2011

Last Update

October 30 2013

Active Locations (1)

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1

Emory University

Atlanta, Georgia, United States, 30322