Status:
UNKNOWN
Non-Invasive Diagnostic and Functional Evaluation of Cardiac Involvement in Patients With Systemic Sclerosis
Lead Sponsor:
Medical University of Warsaw
Conditions:
Systemic Sclerosis
Eligibility:
All Genders
18+ years
Brief Summary
The aim of this study was to assess serum N-terminal proBNP (NT-proBNP) in systemic sclerosis patients and to establish whether it reflects the severity of RV overload.
Detailed Description
Elevated serum brain natriuretic peptide (BNP) levels released from myocytes of ventricles upon stretch have been found in patients with isolated right ventricular (RV) pressure overload. However, lim...
Eligibility Criteria
Inclusion
- Clinical diagnosis of systemic sclerosis
Exclusion
- Cardiovascular disorders other than pulmonary hypertension
- Significant pulmonary function abnormalities
- Impaired renal function
Key Trial Info
Start Date :
April 1 2006
Trial Type :
OBSERVATIONAL
End Date :
April 1 2010
Estimated Enrollment :
100 Patients enrolled
Trial Details
Trial ID
NCT00453752
Start Date
April 1 2006
End Date
April 1 2010
Last Update
March 29 2007
Active Locations (1)
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1
Michał Ciurzyński
Warsaw, Lindleya 4, Poland, 02-005